GETTING THE MOST FROM LYRICA

It’s important to work closely with your doctor and to keep track of how you are feeling and doing. You may feel side effects before you start seeing results. Remember to talk to your doctor so adjustments to your dosage can be made if needed.

Your doctor can adjust your dose to help you get the most from treatment.

RECOMMENDED LYRICA DOSING

Adults (17 years and older):

  • Start with 75 mg 2 times a day or 50 mg 3 times a day (For a total of 150 mg/day)
  • Dosage may be increased based on efficacy and tolerability
  • Up to 300 mg 2 times a day or 200 mg 3 times a day (For a total of 600 mg/day)

In children, 1 month of age and older, the recommended dosing is based on body weight, shown here in kilograms (kg), and may be given as an oral solution.

Children weighing 30 kg or more:

  • Start with 2.5 mg per kg Divided in 2 or 3 doses a day
  • Dosage may be increased based on efficacy and tolerability
  • Up to 10 mg per kg Divided in 2 or 3 doses a day
    (not to exceed 600 mg/day)

Children weighing less than 30 kg:

  • Start with 3.5 mg per kg Divided in 3 doses a day for children between 1 month and 4 years of age, or 2 or 3 doses a day for children older than 4 years
  • Dosage may be increased based on efficacy and tolerability
  • Up to 14 mg per kg Divided in 3 doses a day for children between 1 month and 4 years of age, or 2 or 3 doses a day for children older than 4 years

Work with your doctor to figure out the best dosage. Adult patients and children weighing 30kg or more who do not experience sufficient results with the starting dosage may be further increased up to 600 mg per day, based on efficacy and tolerability. Children weighing less than 30kg who do not experience sufficient results with the starting dosage may be further increased up to 14mg/kg/day. Your doctor may continue to make dosing changes as needed. If there are problems with kidney function, your doctor may prescribe a lower dose of LYRICA.

WHAT TO EXPECT WHEN TAKING LYRICA

Across all clinical studies, side effects were generally mild to moderate. Side effects can vary from person to person, so make sure to talk with your doctor about any side effects you may be experiencing.

  • 1–2 weeks
  • 3–4 weeks
  • 5 weeks +
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It’s possible you may begin to feel side effects within the first week. The 2 most common side effects of LYRICA are dizziness and sleepiness. Across all clinical studies, dizziness occurred in 30% of LYRICA patients, compared with 8% of patients taking a placebo and, on average, lasted about 2 to 4 weeks. For some people, this went away over time. For others, these side effects lasted throughout the course of the studies.

If you do experience side effects, your doctor can adjust your dose or provide recommendations to help.

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After the first few weeks of taking LYRICA, follow up with your doctor and start discussing your complete treatment plan, and get any refills you may need.

This is the right time for you to discuss with your doctor how you are doing and any side effects you may feel. Everyone is unique, and may respond to LYRICA differently.

LYRICA is available in multiple strengths. Your doctor can adjust your dose to help you get the most from treatment.

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After 1 to 2 months of taking LYRICA, be sure to continue to keep your doctor informed. This will enable you both to decide the best course of action to help you get the most from your treatment.

Sleepiness occurred in 23% of LYRICA patients, compared with 8% of patients taking a placebo and, on average, lasted about 4 to 8 weeks. For some people, this went away over time. For others, this side effect lasted throughout the course of the studies.

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TALKING TO YOUR DOCTOR

Get helpful tips on how to talk to your doctor about partial onset seizures.

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LYRICA® (pregabalin) Capsules CV co-pay savings card

SAVE ON LYRICA

Eligible patients may pay as little as $4
per Rx with the Co-Pay Savings Card.†

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†Eligible patients may save up to $250 a month for 12 months (maximum annual savings of $3000). If you are enrolled in a state or federally funded prescription insurance program, you may not use this savings card even if you elect to be processed as an uninsured (cash-paying) patient. See Terms and Conditions link at the bottom of this page. This card is not health insurance.

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IMPORTANT SAFETY INFORMATION

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LYRICA is not for everyone. LYRICA may cause serious, even life-threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck, if you have any trouble breathing, or have a rash, hives, or blisters.

Drugs used to treat seizures increase the risk of suicidal thoughts or behavior. LYRICA may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members, or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self-harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA without first talking to your doctor.

Serious breathing problems can occur when LYRICA is taken with other medicines that can cause severe sleepiness or decreased awareness, or when it is taken by someone who already has breathing problems. Watch for increased sleepiness or decreased breathing when starting LYRICA or when the dose is increased. Get help right away if breathing problems occur.

LYRICA may cause swelling of your hands, legs, and feet, which can be serious for people with heart problems. LYRICA may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish, or any changes in your eyesight, including blurry vision or if you have any kidney problems or get dialysis.

Tell your doctor immediately if you are taking opioid painkillers (such as oxycodone), or medicines for anxiety (such as lorazepam) or insomnia (such as zolpidem). You may have a higher chance for dizziness, sleepiness or serious breathing problems if these medicines are taken with LYRICA. Taking LYRICA with opioid pain medicines may lead to death.

Some of the most common side effects of LYRICA are dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of your hands and feet, dry mouth, and feeling “high.” If you have diabetes, tell your doctor about any skin sores.

You may have a higher chance for swelling and hives if you are also taking angiotensin-converting enzyme (ACE) inhibitors, so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking certain diabetes medicines. Do not drink alcohol while on LYRICA. You may have a higher chance for dizziness and sleepiness if you take LYRICA with alcohol, narcotic pain medicines, or medicines for anxiety.

Before you start LYRICA, tell your doctor if you are planning to father a child, if you are pregnant, or plan to become pregnant. Breastfeeding is not recommended while taking LYRICA. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA.

In studies, a specific type of blood vessel tumor was seen in mice. The meaning of these findings in humans is not known.

Do not stop taking LYRICA without talking to your doctor. If you stop suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.

LYRICA is available in doses ranging from 25 mg to 300 mg and as a 20 mg/mL oral solution.

INDICATIONS

LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles in adult patients. LYRICA is also indicated to treat partial-onset seizures in patients 1 month of age and older with epilepsy who take 1 or more other drugs for seizures.

Please see full Prescribing Information and Medication Guide.

LYRICA and LYRICA CR are not for everyone.

LYRICA and LYRICA CR may cause serious, even life-threatening, allergic reactions. Stop taking LYRICA or LYRICA CR and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck, if you have any trouble breathing, or have a rash, hives, blisters, or skin redness.

LYRICA and LYRICA CR may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members, or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self-harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA or LYRICA CR without first talking to your doctor.

Serious breathing problems can occur when LYRICA or LYRICA CR is taken with other medicines that can cause severe sleepiness or decreased awareness or when it is taken by someone who already has breathing problems. Watch for increased sleepiness or decreased breathing when starting LYRICA or LYRICA CR or when the dose is increased. Get help right away if breathing problems occur.

LYRICA and LYRICA CR may cause swelling of your hands, legs, and feet, which can be serious for people with heart problems.

LYRICA and LYRICA CR may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA or LYRICA CR affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish or any changes in your eyesight, including blurry vision or if you have any kidney problems or get dialysis.

Tell your doctor immediately if you are taking opioid painkillers. Taking LYRICA in combination with these medications may reduce central nervous system activity that could lead to death.

Tell your doctor immediately if you are taking any opioid pain medicine (such as oxycodone), tranquilizers or medicines for anxiety (such as lorazepam), or insomnia (such as zolpidem). You may have a higher chance for dizziness and sleepiness or serious breathing problems if these medicines are taken with LYRICA or LYRICA CR. Taking LYRICA or LYRICA CR with opioid pain medicines may lead to death.

Some of the most common side effects of LYRICA CR are dizziness, blurry vision, weight gain, sleepiness, tiredness, swelling of hands and feet, dry mouth, and nausea.

If you have diabetes, tell your doctor about any sores or skin problems.

You may have a higher chance for swelling and hives if you are also taking angiotensin-converting enzyme (ACE) inhibitors, so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking Avandia (rosiglitazone), Avandamet (contains rosiglitazone and metformin), or Actos (pioglitazone). Do not drink alcohol while on LYRICA or LYRICA CR. You may have a higher chance for dizziness and sleepiness if you take LYRICA or LYRICA CR with alcohol, narcotic pain medicines, or medicines for anxiety.

Before you start LYRICA or LYRICA CR, tell your doctor if you are planning to father a child, if you are pregnant, or plan to become pregnant. Breastfeeding is not recommended while taking LYRICA or LYRICA CR. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA or LYRICA CR.

In studies, a specific type of blood vessel tumor was seen in mice. The meaning of these findings in humans is not known.

Do not stop taking LYRICA or LYRICA CR without talking to your doctor. If you stop suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.

LYRICA is available in doses ranging from 25 mg to 300 mg and as a 20 mg/mL oral solution. LYRICA CR is available in doses ranging from 82.5 mg to 330 mg.

INDICATIONS

LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles in adult patients. LYRICA is also indicated to treat partial-onset seizures in patients 1 month of age and older with epilepsy who take 1 or more other drugs for seizures.

LYRICA CR is indicated to treat pain from damaged nerves (neuropathic pain) that happens with diabetes or that follows healing of shingles.

It is not known if LYRICA CR is safe and effective in children.

It is not known if LYRICA CR is effective when used for the treatment of fibromyalgia or when taken with other seizure medicines for adults with partial-onset seizures.

Please see full LYRICA Prescribing Information and Medication Guide.

Please see full LYRICA CR Prescribing Information and Medication Guide.

Offer Terms And Conditions:

By using the Co-Pay Savings Card, you acknowledge that you currently meet the eligibility criteria and will comply with the following terms and conditions:

Patients are not eligible to use this card or participate in this program if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veteran Affairs healthcare, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”). Patient must have private insurance. Offer is not valid for cash-paying patients. The value of this card is limited to $250 per month per prescription (“offering period”) or the amount of your co-pay, whichever is less (maximum annual savings of $3000). This program is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plan or other private health or pharmacy benefit programs. You must deduct the value received under this program from any reimbursement request submitted to your private insurance plan, either directly by you or on your behalf. You are responsible for reporting use of this program to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the program, as may be required. You should not use the program if your insurer or health plan prohibits use of manufacturer co-pay cards. You must be 18 years of age or older to accept this offer. This offer is not valid where prohibited by law.

For Massachusetts residents:This co-pay offer is not valid if an A/B generic is available for Massachusetts residents whose prescriptions are covered in whole or in part by third-party insurance.

For California residents:This co-pay offer is not valid if a generic is available for California residents whose prescriptions are covered in whole or in part by third-party insurance.

Please check with your healthcare professional or insurer to confirm eligibility. This offer cannot be combined with any other savings, free trial or similar offer for the specified prescription. The co-pay card will be accepted only at participating pharmacies. The co-pay card is not health insurance. Offer good only in the US and Puerto Rico. The co-pay card is limited to one per person during this offering period and is not transferable. A co-pay card may not be redeemed more than once per offering period per patient. No other purchase is necessary. Data related to your redemption of the co-pay card may be collected, analyzed, and shared with Viatris, for market research and other purposes related to assessing Viatris’s programs. Data shared with Viatris will be aggregated and de-identified; it will be combined with data related to other co-pay card redemptions and will not identify you. Viatris reserves the right to rescind, revoke, or amend this offer without notice. No membership fee. For more information, visit our website www.LYRICA.com, call 1-866-954-1475, or contact us at 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560.

Offer expires 12/31/2024.

For reimbursement when using a nonparticipating pharmacy/mail order:Pay for prescription, and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: Co-Pay Savings Card, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. Be sure to include a copy of the front of your activated Co-Pay Savings Card, your name and mailing address.

Mobile Program Terms And Conditions

  1. By opting into the Viatris LSAVINGS Mobile program (“Program”), in which you can receive your Co-Pay Savings Card via text, you consent to receive approximately 5 text messages and/or push notifications per month from Viatris Inc. Consent is not a condition of purchase or use of any Viatris product or service. Such messages may be marketing or non-marketing messages and may include, for example, refill reminders, fill confirmation, website information, etc. T-Mobile is NOT liable for delayed or undelivered messages.
  2. To stop receiving text messages, text STOP to 597422. DOING SO WILL ONLY OPT YOU OUT OF THE LSAVINGS MOBILE PROGRAM; you will remain opted into any other Viatris Inc. text message program(s) to which you separately opted in. You may unsubscribe from the digital wallet message Program at any time by disabling push notifications or removing the digital wallet pass from your device for digital wallet programs.
  3. To request more information or to obtain help, text HELP to 597422. You can also call customer service at 1-877-822-7855.
  4. You represent that you are the account holder for the mobile telephone number(s) that you provide to opt into the texting Program. You are responsible for notifying Viatris Inc. immediately if you change your mobile telephone number. You may notify Viatris Inc. of a number change by re-enrolling in the Program.
  5. Message and data rates may apply to each text message sent or received in connection with the texting Program, as provided in your mobile telephone service rate plan, in addition to any applicable roaming charges. Charges are both billed and payable to your mobile service provider or deducted from your prepaid account. Viatris Inc. does not impose a separate fee for sending text messages.
  6. Data obtained from you in connection with this Short Message Service (SMS) texting program may include your telephone number; your carrier’s name; and the date, time, and content of your messages. Viatris Inc. may use this information to contact you and to provide the services you request from us.
  7. You understand that data obtained from you in connection with your registration for, and use of, the Program may include, for example, your phone number, related carrier information, device information, and elements of pharmacy claim information. This data may be used to administer this Program and to provide Program benefits such as savings offers, information about your prescription, refill reminders, as well as Program updates and alerts sent directly to your device. Please read our full corporate Privacy Policy, which is incorporated by reference into these terms.
  8. In addition to the data use practices described in the Privacy Policy, we may send you offer-related push notifications when your device is in the physical proximity of your pharmacy or healthcare provider. This is done through geofencing technology, which is built into your device. Your device’s location will not be known or tracked by Viatris or its service providers. Nonetheless, you may opt out of geofencing and receiving these notifications at any time by (1) disabling location services for your digital wallet app in your device’s settings, (2) disabling notifications (i.e., automatic updates) within the digital wallet app, or (3) removing the eCard from your digital wallet by selecting “Remove Pass” within the digital wallet app.
  9. Viatris Inc. will not be liable for any delays in the receipt of any SMS messages, as delivery is subject to effective transmission from your network operator.
  10. The service is available only on these US participating mobile carriers: Verizon Wireless, Sprint, Nextel, Boost Mobile, T-Mobile, AT&T, Alltel, ACS Wireless, Bluegrass Cellular, Carolina West Wireless, Cellcom, Cellular One of East Central Illinois (ECIT), Cincinnati Bell, Cricket Wireless, C Spire Wireless, Duet IP (AKA Max/Benton/Albany), Element Mobile, Epic Touch, GCI Communication, Golden State Cellular, Hawkeye (Chat Mobility), Hawkeye (NW Missouri Cellular), Illinois Valley Cellular (IVC), Inland Cellular, iWireless, Keystone Wireless (Immix/PC Management), MetroPCS, Mobi PCS, Mosaic Telecom, MTPCS/Cellular One (Cellone Nation), Nex-Tech Wireless, nTelos, Panhandle Telecommunications, Pioneer, Plateau, Revol Wireless, Rina-Custer, Rina-All West, Rina-Cambridge Telecom Coop, Rina-Eagle Valley Comm, Rina-Farmers Mutual Telephone Co, Rina-Nucla Nutria Telephone Co, Rina-Silver Star, Rina-South Central Comm, Rina-Syringa, Rina-UBET, Rina-Manti, Simmetry Wireless, South Canaan (Cellular One of NEPA), Thumb Cellular, Union Wireless, United Wireless, U.S. Cellular, Viaero Wireless, Virgin Mobile, and West Central Wireless (includes Five Star Wireless).
  11. You agree to indemnify Viatris Inc. and parties texting on its behalf in full for all claims, expenses, and damages related to or caused in whole or in part by your failure to notify us if you change your telephone number, including but not limited to all claims, expenses, and damages related to or arising under the Telephone Consumer Protection Act.
  12. Viatris Inc. may suspend or terminate your receipt of text messages if it believes you are in breach of these SMS Terms and Conditions. Your receipt of text messages is also subject to termination in the event that your mobile telephone service terminates or lapses. Viatris Inc. reserves the right to modify or discontinue, temporarily or permanently, all or any part of the text messaging services you receive, with or without notice.
  13. Viatris Inc. may revise, modify, or amend these SMS Terms and Conditions at any time. Any such revision, modification, or amendment shall take effect when it is posted to Viatris Inc.’s website. You agree to review these SMS Terms and Conditions periodically to ensure that you are aware of any changes. Your continued consent to receive text messages will indicate your acceptance of those changes.

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IMPORTANT SAFETY INFORMATION

LYRICA is not for everyone. LYRICA may cause serious, even life-threatening, allergic reactions. Stop taking LYRICA and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck, if you have any trouble breathing, or have a rash, hives, or blisters.

Drugs used to treat seizures increase the risk of suicidal thoughts or behavior. LYRICA may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members, or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self-harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA without first talking to your doctor.

Serious breathing problems can occur when LYRICA is taken with other medicines that can cause severe sleepiness or decreased awareness, or when it is taken by someone who already has breathing problems. Watch for increased sleepiness or decreased breathing when starting LYRICA or when the dose is increased. Get help right away if breathing problems occur.

LYRICA may cause swelling of your hands, legs, and feet, which can be serious for people with heart problems. LYRICA may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish, or any changes in your eyesight, including blurry vision or if you have any kidney problems or get dialysis.

Tell your doctor immediately if you are taking opioid painkillers (such as oxycodone), or medicines for anxiety (such as lorazepam) or insomnia (such as zolpidem). You may have a higher chance for dizziness, sleepiness or serious breathing problems if these medicines are taken with LYRICA. Taking LYRICA with opioid pain medicines may lead to death.

Some of the most common side effects of LYRICA are dizziness, blurry vision, weight gain, sleepiness, trouble concentrating, swelling of your hands and feet, dry mouth, and feeling “high.” If you have diabetes, tell your doctor about any skin sores.

You may have a higher chance for swelling and hives if you are also taking angiotensin-converting enzyme (ACE) inhibitors, so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking certain diabetes medicines. Do not drink alcohol while on LYRICA. You may have a higher chance for dizziness and sleepiness if you take LYRICA with alcohol, narcotic pain medicines, or medicines for anxiety.

Before you start LYRICA, tell your doctor if you are planning to father a child, if you are pregnant, or plan to become pregnant. Breastfeeding is not recommended while taking LYRICA. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA.

In studies, a specific type of blood vessel tumor was seen in mice. The meaning of these findings in humans is not known.

Do not stop taking LYRICA without talking to your doctor. If you stop suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.

LYRICA is available in doses ranging from 25 mg to 300 mg and as a 20 mg/mL oral solution.

INDICATIONS

LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles in adult patients. LYRICA is also indicated to treat partial-onset seizures in patients 1 month of age and older with epilepsy who take 1 or more other drugs for seizures.

Please see full Prescribing Information and Medication Guide.

LYRICA and LYRICA CR are not for everyone.

LYRICA and LYRICA CR may cause serious, even life-threatening, allergic reactions. Stop taking LYRICA or LYRICA CR and call your doctor right away if you have any signs of a serious allergic reaction. Some signs are swelling of your face, mouth, lips, gums, tongue, throat or neck, if you have any trouble breathing, or have a rash, hives, blisters, or skin redness.

LYRICA and LYRICA CR may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Patients, family members, or caregivers should call the doctor right away if they notice suicidal thoughts or actions, thoughts of self-harm, or any unusual changes in mood or behavior. These changes may include new or worsening depression, anxiety, restlessness, trouble sleeping, panic attacks, anger, irritability, agitation, aggression, dangerous impulses or violence, or extreme increases in activity or talking. If you have suicidal thoughts or actions, do not stop LYRICA or LYRICA CR without first talking to your doctor.

Serious breathing problems can occur when LYRICA or LYRICA CR is taken with other medicines that can cause severe sleepiness or decreased awareness or when it is taken by someone who already has breathing problems. Watch for increased sleepiness or decreased breathing when starting LYRICA or LYRICA CR or when the dose is increased. Get help right away if breathing problems occur.

LYRICA and LYRICA CR may cause swelling of your hands, legs, and feet, which can be serious for people with heart problems.

LYRICA and LYRICA CR may cause dizziness and sleepiness. You should not drive or work with machines until you know how LYRICA or LYRICA CR affects you. Also, tell your doctor right away about muscle pain or problems along with feeling sick and feverish or any changes in your eyesight, including blurry vision or if you have any kidney problems or get dialysis.

Tell your doctor immediately if you are taking opioid painkillers. Taking LYRICA in combination with these medications may reduce central nervous system activity that could lead to death.

Tell your doctor immediately if you are taking any opioid pain medicine (such as oxycodone), tranquilizers or medicines for anxiety (such as lorazepam), or insomnia (such as zolpidem). You may have a higher chance for dizziness and sleepiness or serious breathing problems if these medicines are taken with LYRICA or LYRICA CR. Taking LYRICA or LYRICA CR with opioid pain medicines may lead to death.

Some of the most common side effects of LYRICA CR are dizziness, blurry vision, weight gain, sleepiness, tiredness, swelling of hands and feet, dry mouth, and nausea.

If you have diabetes, tell your doctor about any sores or skin problems.

You may have a higher chance for swelling and hives if you are also taking angiotensin-converting enzyme (ACE) inhibitors, so tell your doctor if you are taking these medications. You may have a higher chance of swelling of your hands or feet or gaining weight if you are also taking Avandia (rosiglitazone), Avandamet (contains rosiglitazone and metformin), or Actos (pioglitazone). Do not drink alcohol while on LYRICA or LYRICA CR. You may have a higher chance for dizziness and sleepiness if you take LYRICA or LYRICA CR with alcohol, narcotic pain medicines, or medicines for anxiety.

Before you start LYRICA or LYRICA CR, tell your doctor if you are planning to father a child, if you are pregnant, or plan to become pregnant. Breastfeeding is not recommended while taking LYRICA or LYRICA CR. If you have had a drug or alcohol problem, you may be more likely to misuse LYRICA or LYRICA CR.

In studies, a specific type of blood vessel tumor was seen in mice. The meaning of these findings in humans is not known.

Do not stop taking LYRICA or LYRICA CR without talking to your doctor. If you stop suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, increased sweating, or you may feel anxious. If you have epilepsy, you may have seizures more often.

LYRICA is available in doses ranging from 25 mg to 300 mg and as a 20 mg/mL oral solution. LYRICA CR is available in doses ranging from 82.5 mg to 330 mg.

INDICATIONS

LYRICA is indicated to treat fibromyalgia, diabetic nerve pain, spinal cord injury nerve pain, and pain after shingles in adult patients. LYRICA is also indicated to treat partial-onset seizures in patients 1 month of age and older with epilepsy who take 1 or more other drugs for seizures.

LYRICA CR is indicated to treat pain from damaged nerves (neuropathic pain) that happens with diabetes or that follows healing of shingles.

It is not known if LYRICA CR is safe and effective in children.

It is not known if LYRICA CR is effective when used for the treatment of fibromyalgia or when taken with other seizure medicines for adults with partial-onset seizures.

Please see full LYRICA Prescribing Information and Medication Guide.

Please see full LYRICA CR Prescribing Information and Medication Guide.